Professional Supplier O-Tolunitrile 2-Methylbenzonitrile CAS 529-19-1

• Customization: Available
• CAS No.: 529-19-1
• Formula: C8h7n
• Model NO.: 99%
• EINECS: 208-451-7
• Type: Synthesis Material Intermediates
• Appearance: Liquid
• Quality: Industrial
• Colour: Colorless
• Specification: ≥ 99%
• Trademark: JinYu
• Origin: China

Product Description

Product Description

o-Tolunitrile (2-Methylbenzonitrile) - Product Overview

CAS No.: 529-19-1
EINECS No.: 208-452-0
Chemical Formula: C8H7N
Molecular Weight: 117.15 g/mol
Synonyms: 2-Methylbenzonitrile, o-Cyanotoluene, o-Methylbenzonitrile

 

1. Product Description

o-Tolunitrile is a colorless to pale yellow liquid with a characteristic pungent, aromatic odor. It is a nitrile compound derived from toluene. It is slightly soluble in water but readily soluble in organic solvents such as ethanol, ether, and benzene. It is a versatile intermediate used in the synthesis of various pharmaceuticals, agrochemicals, and dyes.

 

2. Key Features & Benefits

o-Tolunitrile offers several important properties for industrial applications:

• Reactivity: The cyano group (-CN) is highly reactive, allowing for hydrolysis to carboxylic acids, reduction to amines, and other transformations.
• Isomeric Specificity: Its ortho structure provides specific steric and electronic effects required in certain syntheses (e.g., the synthesis of chiral drugs).
• Stability: Exhibits good chemical stability under normal storage conditions.
• Purity: Available in high-purity grades suitable for pharmaceutical API synthesis.

 

3. Typical Physical and Chemical Properties

(Typical values are for reference only; please refer to the specific COA for batch analysis)

 

Property	Specification	Test Method
Appearance	Colorless to pale yellow liquid	Visual
Purity (GC)	≥ 99.0%	GC
Melting Point	-13°C	-
Boiling Point	205 - 207°C	-
Flash Point (Closed Cup)	85°C (185°F)	ASTM D93
Density (20°C)	0.984 - 0.988 g/cm³	ASTM D4052
Refractive Index (20°C)	1.524 - 1.526	ASTM D1218
Water Solubility	Insoluble	-
Color (APHA)	≤ 50	Pt-Co Scale

 

4. Main Applications

o-Tolunitrile is widely used as an intermediate in the production of fine chemicals:

• Pharmaceuticals:
  • Antidepressants: It is a key raw material for the synthesis of Sertraline (Zoloft), a widely used selective serotonin reuptake inhibitor (SSRI).
  • Other Drugs: Used in the production of antihistamines, antipsychotics, and other pharmaceutical intermediates.
• Agrochemicals:
  • Insecticides/Herbicides: Used in the synthesis of various pesticides, including pyrethroid insecticides and herbicides.
• Dyes & Pigments:
  • Intermediate: Used in the production of azo dyes, anthraquinone dyes, and other organic pigments.
• Other Applications:
  • Chemical Synthesis: Used as a starting material for the production of benzyl alcohols, benzylamines, and other organic compounds.
  • Flavors & Fragrances: Used in the synthesis of certain fragrance compounds.
  •  
   

5. Packaging & Storage

• Packaging:
  • Drums: 180 kg or 200 kg net weight (seamless steel drums).
  • IBC Totes: 1,000 kg net weight (Intermediate Bulk Containers).
  • Bulk: In ISO tank containers.
• Storage Conditions:
  • Store in a cool, dry, and well-ventilated warehouse.
  • Keep containers tightly closed to prevent contamination and moisture absorption.
  • Temperature: Ideally stored below 30°C.
  • Incompatibilities: Keep away from strong acids, strong bases, and strong oxidizing agents.
   

 

6. Handling & Safety

• Flammability: o-Tolunitrile is combustible (Category 4). Keep away from heat and open flames.
• Health Hazards:
  • Skin: Causes skin irritation. May be absorbed through the skin, leading to systemic effects.
  • Eyes: Causes serious eye irritation and damage.
  • Inhalation: Inhalation of vapors may cause respiratory tract irritation, coughing, and shortness of breath.
  • Ingestion: Harmful if swallowed. May cause nausea, vomiting, and abdominal pain.
• Precautions:
  • PPE: Wear appropriate personal protective equipment, including safety glasses, chemical-resistant gloves (nitrile or neoprene), a lab coat, and a respirator.
  • Handling: Avoid contact with skin and eyes. Use in a fume hood or well-ventilated area.
  • First Aid: In case of contact, immediately flush skin or eyes with plenty of water for at least 15 minutes. If swallowed, do not induce vomiting; seek medical attention immediately.

Product Parameters

 

Packaging & Shipping

Liquid products	Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons .
Solid products	Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg.

Packaging can be customized according to customer requirements.

Company Profile

Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.

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