Customization: | Available |
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CAS No.: | 675-20-7 |
Formula: | C5h9no |
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Basic Information
Product Name: 2-Piperidinone
Alias: α-Piperidinone; Hexahydro-2-pyridinone
Chemical Formula: C5H9NO
CAS Number: 675-20-7
Molecular Weight: 99.13 g/mol
Appearance:Colorless to light yellow liquid or crystals at room temperature (liquid near melting point), highly hygroscopic.
Melting Point: 26-28 °C
Boiling Point: 218-220 °C (at atmospheric pressure)
Solubility: Highly soluble in polar solvents such as water, ethanol, diethyl ether, and acetone;Slightly soluble in nonpolar solvents like benzene.
Applications
Pharmaceutical Industry
Pharmaceutical Intermediates:
Key raw material for synthesizing antidepressants (e.g., milnacipran), anticonvulsants, and local anesthetics (e.g., piperocaine);
Used in the preparation of ACE inhibitor antihypertensive drugs.
Drug Carrier: Its polarity and solubility make it a cosolvent for injections or a component of sustained-release formulations.
Organic Synthesis
Solvent: High boiling point and strong polarity, used for dissolving polar organic compounds (e.g., as a reaction medium in polymer synthesis);
Chiral Synthesis: Acts as a chiral auxiliary or ligand in asymmetric synthesis reactions (e.g., Michael addition, Diels-Alder reaction).
Agriculture and Daily Chemicals
Pesticide Intermediates: Synthesis of herbicides and insecticides (e.g., heterocyclic pesticides containing piperidine structures);
Surfactants: Reacts with fatty acids to form amide-based surfactants for detergents or emulsifiers.
Materials Science
Polymer Additives: Improves the flexibility and thermal stability of polyamides (nylons);
Ionic Liquid Precursor: Prepares functional ionic liquids via alkylation for catalysis or energy storage.
Safety and Storage
Hazards:
Irritant: Stimulates skin, eyes, and respiratory tract; high-concentration inhalation may cause headache and nausea;
Low Toxicity: LD50 (rat, oral) ~2000 mg/kg, classified as a low-toxic compound.
Safety Measures:
Wear gloves and goggles during operation; use in a well-ventilated area;
If skin contact occurs, rinse with soapy water immediately; if ingested, drink warm water to induce vomiting and seek medical attention.
Storage Conditions:
Store in a sealed container in a cool, dry place, away from oxidizers and strong acids, and protect from moisture.
Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.