| Customization: | Available |
|---|---|
| CAS No.: | 79-37-8 |
| Formula: | C2cl2o2 |
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
Basic Information
Product Name: Oxalyl Chloride, Ethanedioyl Chloride
Molecular Formula: C2Cl2O2
Molecular Weight: 126.93 g/mol
CAS Number: 79-37-8
Appearance: Colorless fuming liquid with a strong pungent odor (similar to hydrogen chloride).
Density: 1.48 g/mL (25°C)
Boiling Point: 63-64°C
Melting Point: -12°C
Solubility: Reacts violently with water; soluble in organic solvents like diethyl ether, benzene, and chloroform.
Main Applications
(1) Organic Synthesis
Core Uses:
Acyl Chloride Preparation: Efficient chlorinating agent for converting carboxylic acids and phenols into acyl chlorides (e.g., synthesis of benzoyl chloride, acetyl chloride), widely used in pharmaceuticals, pesticides, and fragrances.
Carboxylic Acid Activation: Activates amino acids in peptide synthesis to facilitate peptide bond formation.
Dehydrating Agent: Used to prepare acid anhydrides (e.g., phthalic anhydride) or nitriles (via amide dehydration).
Typical Reactions:
Reaction with Grignard reagents to form ketones (e.g., synthesis of diphenyl ketone derivatives).
Reaction with amines to prepare amides (e.g., synthesis of nicotinamide, a pesticide intermediate).
(2) Pharmaceutical Industry
Drug Intermediates:
Synthesis of antibiotics (e.g., acylation of penicillin side chains) and anticancer drugs (e.g., precursors of oxaliplatin).
Preparation of key intermediates for non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen derivatives.
(3) Pesticides and Dyes
Pesticides: Used in synthesizing herbicides (e.g., intermediates for glyphosate) and insecticides (e.g., acylation of organophosphorus pesticides).
Dyes: Involved in synthesizing intermediates for anthraquinone and azo dyes, enhancing color fastness and chromogenic properties.
(4) Other Fields
Polymer Materials: Acts as an initiator or chain terminator in polymerization reactions for preparing polyesters and polyamides.
Surfactants: Precursor for synthesizing carboxylate surfactants (e.g., fatty acid methyl ester sulfonates).
Safety and Handling
Hazards
Health Risks:
Corrosive: Causes burns on contact with skin or mucous membranes (immediate rinsing with water is required).
Inhalation Risk: Vapors of HCl and oxalyl chloride irritate the respiratory tract, potentially causing pulmonary edema (wear a gas mask).
Environmental Hazard: Hydrolysis products (HCl and oxalic acid) are harmful to water bodies; prevent leakage into the environment.
Safe Handling
Protective Equipment:
Wear corrosion-resistant gloves (e.g., nitrile rubber), goggles, and chemical-resistant clothing.
Operate in a fume hood to avoid inhaling vapors.
Storage and Transportation:
Store in a sealed container in a dry, cool place, away from water, alcohols, and amines.
Transport in corrosion-resistant containers (e.g., glass bottles or metal drums lined with plastic), labeled as "Corrosive" and "Reacts with Water."
Emergency Procedures
Leakage: Cover with dry sand, collect, and neutralize with sodium carbonate solution; avoid direct water rinsing.
Firefighting: Do not use water; use dry powder or carbon dioxide extinguishers (to prevent HCl formation).
Regulations and Storage
Regulatory Control:
Classified as a hazardous chemical (UN 3265, Class 8 Corrosive Substance), subject to regulations like China's Regulations on the Safety Management of Hazardous Chemicals and GHS classification standards.
Shelf Life: Can be stored long-term if sealed; use promptly after opening and protect from moisture.
| Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
| Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.
){kind=link}