Customization: | Available |
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CAS No.: | 128-08-5 |
Formula: | C4h4brno2 |
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Basic Information
Product Name: N-Bromosuccinimide (NBS)
Chemical Formula: C4H4BrNO2
Molar Mass: 177.98 g/mol
CAS Number: 128-08-5
Appearance: White to off-white crystalline powder with a slight bromine odor.
Melting Point: 180-182°C (decomposes)
Density: 2.098 g/cm³ (25°C)
Solubility: Insoluble in water; slightly soluble in benzene, toluene, and chloroform; soluble in acetone and ethyl acetate.
Weakly dissociates to release bromide ions in polar solvents (e.g., DMF, DMSO).
Applications
Organic Synthesis
Allylic/Benzylic Bromination: Prepares key intermediates (e.g., for pharmaceuticals and pesticides).
Oxidation of Alcohols: Converts alcohols to aldehydes/ketones in DMSO (e.g., modified Swern oxidation).
Cyclization Reactions: Facilitates intramolecular bromocyclization to form heterocycles (e.g., indoles, furans).
Polymer Industry: Acts as an initiator or chain transfer agent in radical polymerization (e.g., synthesizing brominated polystyrene).
Pharmaceuticals and Agrochemicals: Used in synthesizing antimicrobial agents (e.g., bromoamides) and plant growth regulators.
Analytical Chemistry: Quantifies thiols (-SH) via titration: NBS reacts stoichiometrically with thiols to release bromine, which is then titrated.
Safety and Storage
Hazards:
Irritant/Toxic: Powder irritates eyes, respiratory tract, and skin; ingestion/inhalation may cause nausea/vomiting.
Oxidizing: Reacts violently with reducing agents (e.g., thiosulfates, phenols) and flammables (e.g., ethanol).
Safety Measures:
Use in a fume hood; wear goggles, gloves (e.g., nitrile), and a dust mask.
For skin/eye contact, flush with water immediately; if ingested, rinse mouth and seek medical help (do not induce vomiting).
Storage: Store in a sealed container in a cool, dry place, away from moisture, heat, and reducers. Classified as Corrosive Substance (UN 3261) for transport; avoid mixing with food or daily items.
Environmental Impact
Degradation: Hydrolysis products (HBr and succinimide) degrade slowly in the environment, but high bromide levels may harm aquatic ecosystems (e.g., inhibit algae growth).
Waste Disposal: Neutralize with sodium carbonate solution before disposing as hazardous waste; never discharge into drains.
Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.