| Customization: | Available |
|---|---|
| CAS No.: | 1185-53-1 |
| Formula: | C4h12clno3 |
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Basic Information
Product Name: Tris(hydroxymethyl)aminomethane Hydrochloride. It is also abbreviated as Tris - HCl
CAS Number: 1185 - 53 - 1.
Molecular Formula: C4H12ClNO3.
Molecular Weight: 157.596 g/mol.
Appearance: It is a white crystalline powder, odorless, and easily absorbs moisture.
Solubility: It is highly soluble in water (the solubility is about 550 g/L at 25 °C), slightly soluble in ethanol, and insoluble in organic solvents such as ether. The aqueous solution is acidic, and the pH varies significantly with concentration. For example, the pH of a 0.1 mol/L solution is about 4.5.
Application Areas
Biochemical Buffer: It is often used to prepare buffer systems with a pH range of 7.5 - 9.0, such as Tris - HCl buffer. It is suitable for nucleic acid extraction, protein electrophoresis (such as SDS - PAGE), enzyme reactions, etc. Its advantages include strong buffering capacity (the pKa is about 8.1 at 25 °C) and good compatibility with biological molecules.
Medicine and Cosmetics: As an acid - base regulator, it is used in drug preparations (such as injections, eye drops) and skin - care products to stabilize the pH.
Molecular Biology Experiments: It is used to prepare DNA/RNA extraction reagents (such as TE buffer: Tris - HCl + EDTA), reverse - transcription reaction buffers, etc.
Analytical Chemistry: It is used as a standard substance for acidity titration or to prepare ionic - strength regulators.
Safety and Handling Precautions
Hazards: The dust is irritating to the respiratory tract, eyes, and skin. High - concentration solutions may cause burns. Although it has little harm to water bodies, direct discharge into natural water systems in large quantities should be avoided.
Protective Measures: When operating, wear a mask, gloves, and goggles, and work in a well - ventilated area to avoid inhaling dust or contacting the skin and mucous membranes. Store it in a sealed container, protect it from moisture, and keep it away from strong oxidants and alkaline substances.
Emergency Treatment: If it comes into contact with the skin, immediately rinse it with a large amount of clean water. If it gets into the eyes, rinse it with flowing clean water for 15 minutes and seek medical attention. In case of ingestion, drink enough warm water to induce vomiting (follow medical advice) and seek medical attention with the drug label.
| Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
| Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.
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