| Customization: | Available |
|---|---|
| CAS No.: | 75-36-5 |
| Formula: | C2h3clo |
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Basic Information
Product Name: Acetyl Chloride, Acetic Chloride
Molecular Formula: C2H3ClO
Molar Mass: 78.5 g/mol
CAS Number: 75-36-5
Appearance: Colorless, transparent, fuming liquid with a strong pungent odor (similar to hydrochloric acid).
Boiling Point: 51-52°C (highly volatile).
Density: 1.104 g/mL (at 20°C).
Solubility: Reacts violently with water; soluble in organic solvents like ethanol, diethyl ether, and chloroform.
Main Applications
Organic Synthesis Intermediate
Ester Synthesis: Used to prepare acetates (e.g., ethyl acetate, methyl acetate), widely applied in fragrances, coatings, and solvents.
Amide Synthesis: A critical step in producing pharmaceuticals (e.g., penicillin antibiotics) and pesticides (e.g., insecticide intermediates).
Acylating Reagent: Acts as an acyl donor in organic reactions for the acylation of phenols, amines, and alcohols (e.g., in ibuprofen synthesis).
Pharmaceutical and Pesticide Industries
Synthesizes intermediates for sedatives, analgesics, and other drugs.
Prepares pesticide molecules with acyl groups (e.g., herbicides, fungicides).
Dye and Fragrance Industries
Manufactures acetyl dyes (e.g., disperse dyes).
Produces food flavorings (e.g., benzyl acetate for fruit fragrances).
Other Uses
Serves as an additive in lithium battery electrolytes to improve battery performance.
Activates carboxylic acids in laboratories (converts carboxylic acids to acyl chlorides for enhanced reactivity).
Safety and Hazards
Hazard Classification (GHS):
Signal Word: Danger
Hazard Symbols: Corrosion, Inhalation Hazard
Hazard Statements:
H314: Causes severe skin burns and eye damage.
H335: May cause respiratory irritation.
H317: May cause allergic skin reactions.
Safe Handling:
Protective Gear: Wear corrosion-resistant gloves, goggles, and lab coats; operate in a fume hood (to avoid inhaling HCl vapors).
Storage: Store in a sealed container in a cool, dry place, away from water, alkalis, and alcohols (use glass or metal containers; avoid plastics).
Spill Management: Absorb with dry sand or vermiculite, avoid water contact, then neutralize residues with dilute alkali (e.g., sodium carbonate).
First Aid:
Skin Contact: Flush with plenty of water for at least 15 minutes; seek medical help.
Eye Contact: Rinse with saline solution; seek medical help.
Inhalation: Move to fresh air, maintain breathing; provide oxygen or artificial respiration if needed; seek medical help.
Key Notes
Corrosive Risk: Avoid direct contact with skin/mucus membranes; follow strict safety protocols.
Environmental Impact: HCl from hydrolysis can contaminate water; wastewater must be neutralized with alkali.
Summary
Acetyl chloride is a vital acylating reagent and organic synthesis intermediate, widely used in pharmaceuticals, pesticides, and fragrances due to its high reactivity. Despite its utility, its strong corrosiveness and toxicity demand strict safety measures in production, use, and storage to prevent accidents and environmental harm.
| Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
| Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.
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