| Customization: | Available |
|---|---|
| CAS No.: | 462-34-0 |
| Formula: | Bf3.C4h8o |
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Basic Information
Product Name: Boron trifluoride tetrahydrofuran complex
Common Alias: BF3.THF complex
Chemical Formula: BF3.C4H8O (1:1 complex with tetrahydrofuran, THF)
Molecular Weight: 141.98 g/mol
CAS Number: 109-63-7
Appearance: Colorless to light yellow liquid (highly hygroscopic)
Density: ~1.13 g/mL (at 25°C)
Boiling Point: 55-60°C (decomposes gradually; THF boils at 66°C, but the complex has stronger intermolecular forces)
Solubility: Miscible with THF, dichloromethane, chloroform, and other organic solvents; Reacts violently with water and alcohols
Vapor Pressure: Low (volatile, but less than pure THF due to complex formation)
Applications
Organic Synthesis Catalyst
Friedel-Crafts Reactions: Promotes alkylation/acylation of aromatic compounds (e.g., synthesizing aryl ketones).
Epoxide Ring-Opening: Catalyzes regioselective opening of epoxides (e.g., in polymer synthesis or drug intermediates).
Diels-Alder Reactions: Enhances reaction rates and stereoselectivity in cycloadditions.
Polymerization Reactions: Initiates cationic polymerization of olefins (e.g., isobutylene) or THF itself.
Pharmaceutical and Fine Chemical Production
Used in synthesizing pharmaceutical intermediates (e.g., heterocyclic compounds, natural product derivatives).
Example: Catalyzing cyclization reactions in alkaloid synthesis.
Polymer Chemistry
As a catalyst in synthesizing polyethers (e.g., poly(THF)) or polyester resins.
Laboratory Reagent
A common Lewis acid in academic research, offering better solubility and handling compared to gaseous BF3 or BF3·ether complexes.
Safety and Handling
1. Hazards
Toxicity: Releases HF upon hydrolysis, which is highly toxic (corrosive to skin, eyes, and respiratory tract; can cause systemic fluoride poisoning).
Corrosiveness: The complex itself is corrosive and may cause severe burns.
Fire Hazard: THF is flammable; vapor forms explosive mixtures with air.
2. Safety Precautions
Personal Protection: Wear chemical-resistant gloves (e.g., nitrile), goggles, and a lab coat. Use a fume hood to avoid inhaling vapors.
Anhydrous Conditions: Store in airtight containers under dry nitrogen; avoid exposure to moisture or air.
Spill Handling: Absorb spills with inert, non-combustible materials (e.g., sand), then neutralize with alkaline agents (e.g., sodium bicarbonate) in a controlled manner (note: HF neutralization produces toxic fluorides, requiring proper waste disposal).
Fire Extinguishing: Use dry chemical, CO2, or alcohol-resistant foam; water may accelerate hydrolysis and release HF.
3. Storage
Store in a cool, dry, well-ventilated area, away from moisture, alkalis, and reactive metals (e.g., sodium, potassium).
Keep containers tightly sealed; avoid long-term exposure to air.
| Liquid products | Drum of 5kg ,10 kg ,25 kg ,50 kg 200 kg ,250 kg . 1000 kg IBC drum. TANK with 20 tons ,25 tons . |
| Solid products | Bag of 1 kg ,2 kg ,5 kg ,25 kg ,500kg ,1000 kg . Drum of 25 kg and 50 kg. |
Packaging can be customized according to customer requirements.
Qingdao Jinyu Chemical Co., LTD,which is located in Qingdao City, China, with registered capital of RMB 10 million, is a dynamic chemical import and export enterprise with customer demand as its own responsibility. The founder has been engaged in the chemical industry for more than 20 years. With professional technical and marketing personnel, diversified cooperative factories with synthetic technology and efficient logistics management, we provide services to customers all over the world. After years of hard work, we have selected a number of excellent chemical production cooperative enterprises in China. These enterprises have their own advantages in different chemical synthesis fields. They have passed the strict inspection of suppliers by many customers and formed a long-term and stable strategic partnership with customers. With our partners' excellent equipment, well-trained employees and mature technology, we also continue to provide customers with more products.
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